You want to test whether a particular allele of the Î²-interferon gene (the a3 allele) is responsible for an immune deficiency disease. Using an assay for a restriction site present in the a3 allele and absent in other Î²-interferon alleles, you have mapped the inheritance of the a3 allele and the disease phenotype in a large number of affected families. You find that the map distance between the Î²-interferon gene and the disease phenotype is 2 cM. (In other words, in 2% of cases, children inherit the disease allele without inheriting the a3 allele.) Which one of the following conclusions can you make from these results?
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